A new X-ray telescope run by the Japan Aerospace Agency has gone silent a little more than a month after its launch. JAXA reported online March 27 that the telescope, ASTRO-H (aka Hitomi), stopped communicating with Earth. U.S. Strategic Command’s Joint Space Operations Center also reported seeing five pieces of debris alongside the satellite on March 26.
Attempts to figure out what went wrong with the spacecraft, which launched February 17, have not been successful. Up until now though, ASTRO-H seemed to be functioning. In late February, mission operators successfully switched on the spacecraft’s cooling system and tested some of its instruments.
ASTRO-H carries four instruments to study cosmic X-rays over an energy range from 0.3 to 600 kiloelectron volts. By studying X-rays, astronomers hope to learn more about some of the more feisty denizens of the universe such as exploding stars, gorging black holes, and dark matter swirling around within galaxy clusters. Earth’s atmosphere absorbs X-rays, so the only way to see them is to put a telescope in space.
Clownfish and anemones depend on one another. The stinging arms of the anemones provide clownfish with protection against predators. In return, the fish keep the anemone clean and provide nutrients, in the form of poop. Usually, several individual clownfish occupy a single anemone — a large and dominant female, an adult male and several subordinates — all from the same species. But with 28 species of clownfish and 10 species of anemone, there can be a lot of competition for who gets to occupy which anemone.
In the highly diverse waters of the Coral Triangle of Southeast Asia, however, clownfish have figured out how to share, researchers report March 30 in the Proceedings of the Royal Society B. Anemones in these waters are often home to multiple species of clownfish that live together peacefully.
From 2005 to 2014, Emma Camp, of the University of Technology Sydney and colleagues gathered data on clownfish and their anemone homes from 20 locations that had more than one species of clownfish residents. In 981 underwater survey transects, they encountered 1,508 clownfish, 377 of which lived in groups consisting of two or more fish species in a single anemone.
Most of those cohabiting clownfish could be found in the waters of the Coral Triangle, the team found, with the highest levels of species cohabitation occurring off Hoga Island in Indonesia. There, the researchers found 437 clownfish from six species living among 114 anemones of five species. Every anemone was occupied by clownfish, and half had two species of the fish.
In general, “when the number of clownfish species exceeded the number of host anemone species, cohabitation was almost always documented,” the researchers write.
The multiple-species groups divvied up space in an anemone similar to the way that a single-species group does, with subordinate fish sticking to the peripheries. That way, those subordinate fish can avoid fights — and potentially getting kicked off the anemone or even dying. “Living on the periphery of an anemone, despite the higher risk of predation, is a better option than having no host anemone,” the team writes.
These multi-species groups might even be better for both of the clownfish species, since they wouldn’t have to compete so much over mates, and perhaps even less over food, if the species had different diets.
This isn’t the first time that scientists have found cohabitation to be an effective strategy in an area of high biodiversity. This has also been demonstrated with scorpions in the Amazon. But it does show how important it is to conserve species in regions such as this, the researchers say — because losing one species can easily wipe out several more.
NEW YORK — Lip-readers’ minds seem to “hear” the words their eyes see being formed. And the better a person is at lipreading, the more neural activity there is in the brain’s auditory cortex, scientists reported April 4 at the annual meeting of the Cognitive Neuroscience Society.
Earlier studies have found that auditory brain areas are active during lipreading. But most of those studies focused on small bits of language — simple sentences or even single words, said study coauthor Satu Saalasti of Aalto University in Finland. In contrast, Saalasti and colleagues studied lipreading in more natural situations. Twenty-nine people read the silent lips of a person who spoke Finnish for eight minutes in a video. “We can all lip-read to some extent,” Saalasti said, and the participants, who had no lipreading experience, varied widely in their comprehension of the eight-minute story.
In the best lip-readers, activity in the auditory cortex was quite similar to that evoked when the story was read aloud, brain scans revealed. The results suggest that lipreading success depends on a person’s ability to “hear” the words formed by moving lips, Saalasti said.
It’s official: Zika virus causes microcephaly and other birth defects.
A new analysis by the U.S. Centers for Disease Control and Prevention confirms what many earlier studies had suggested: The virus, typically passed via the bite of an infected mosquito, can travel from a pregnant woman to her fetus and wreak havoc in the brain.
“There is no longer any doubt that Zika causes microcephaly,” CDC director Tom Frieden said in a news briefing Wednesday. The findings, reported April 13 in the New England Journal of Medicine, follow a March 31 report from the World Health Organization that concluded nearly the same thing.
Because the connection between a mosquito-borne illness and such birth defects is so unprecedented, the CDC took time to carefully weigh the evidence, Frieden said. “Never before in history has there been a situation where a bite from a mosquito could result in a devastating malformation.”
In the NEJM analysis, researchers factored in molecular, epidemiological and clinical data, including recent reports of babies born with microcephaly in Colombia. The country has been suffering from a Zika outbreak for months, and thousands of pregnant women have been infected with the virus. Based on what scientists know about the virus, now is about the time they would have expected to see birth defects, said CDC public health researcher and study coauthor Sonja Rasmussen. WHO reports 50 cases of microcephaly in Colombia, seven of which have a confirmed link to Zika.
Researchers still can’t pin down the odds that an infection during pregnancy will lead to microcephaly, though. “What we don’t know right now is if the risk is somewhere in the range of 1 percent or in the range of 30 percent,” Rasmussen said.
Scientists do believe, however, that women who aren’t pregnant would probably clear a Zika infection within eight weeks, and not have problems with future pregnancies, Rasmussen said.
To rewrite an Alanis Morissette song, the brain has a funny way of waking you up (and putting you to sleep). Isn’t it ionic? Some scientists think so.
Changes in ion concentrations, not nerve cell activity, switch the brain from asleep to awake and back again, researchers report in the April 29 Science. Scientists knew that levels of potassium, calcium and magnesium ions bathing brain cells changed during sleep and wakefulness. But they thought neurons — electrically active cells responsible for most of the brain’s processing power — drove those changes. Instead, the study suggests, neurons aren’t the only sandmen or roosters in the brain. “Neuromodulator” brain chemicals, which pace neuron activity, can bypass neurons altogether to directly wake the brain or lull it to sleep by changing ion concentrations.
Scientists hadn’t found this direct connection between ions and sleep and wake before because they were mostly focused on what neurons were doing, says neuroscientist Maiken Nedergaard, who led the study. She got interested in sleep after her lab at the University of Rochester in New York found a drainage system that washes the brain during sleep (SN: 11/16/13, p. 7).When measuring changes in the fluid between brain cells, Nedergaard and colleagues realized that ion changes followed predictable patterns: Potassium ion levels are high when mice (and presumably people) are awake, and drop during sleep. Calcium and magnesium ions follow the opposite pattern; they are higher during sleep and lower when mice are awake. In the study, Nedergaard’s group administered a “wake cocktail” of neuromodulator chemicals to mouse brains. Levels of potassium ions floating between brain cells increased rapidly after the treatment, the researchers found. That ion change happened even when the researchers added tetrodotoxin to stop neuron activity. The results suggest that the brain chemicals — norepinephrine, acetylcholine, dopamine, orexin and histamine — directly affect ion levels with no help from neurons. Exactly how the chemicals manage ion levels still isn’t known. Similar changes happen under anesthesia. When awake mice were anesthetized, potassium ion levels in their brains dropped sharply, while levels of calcium and magnesium rose, the researchers found. As mice awoke from anesthesia, potassium ion levels rose quickly. But calcium and magnesium levels took longer to drop. As a result, the mice “are totally confused,” says Nedergaard. “They bump into their cages, they run around and they don’t know what they are doing.”
Those results may help explain why people are groggy after waking up from anesthesia; their ion levels haven’t returned to “awake” levels yet, says Amita Sehgal, a sleep researcher at the University of Pennsylvania School of Medicine.
Learning more about how ions affect wake and sleep may eventually lead to a better understanding of sleep, consciousness and coma, Nedergaard says.
But, says neuroscientist Chiara Cirelli of the University of Wisconsin‒Madison, practical implications of the work, such as improved sleep drugs, are probably far in the future. “How they make use of it will take some time, but just knowing this is certainly very eye-opening.” It would be interesting to find out what happens to ion concentrations during REM sleep, when neurons are as active as they are when a person is awake, she says.
You wouldn’t expect wardrobe classics like leather jackets or denim jeans at an exhibit celebrating fashion at its most forward. But “#techstyle” at the Museum of Fine Arts in Boston features those sartorial mainstays and others, each with a technological twist.
A feast for the eyes, the diversity of pieces is matched by the diversity of artists and approaches. Yet a single theme unites: The fusion of technology and fashion will increasingly influence both. Visitors are introduced to this theme via a room featuring works by prominent designers already known for merging fashion and tech: A digitally printed silk dress by Alexander McQueen hangs next to a fiberglass “airplane dress” by Hussein Chalayan that has flaps that open and shut via remote control. The largest part of the exhibit focuses on how technology is changing design and construction strategies. In addition to clothes made with mainstream techniques like laser-cutting, several 3-D printed garments are on display. These include a kinematic dress made of more than 1,600 interlocking pieces that can be customized to a wearer’s body via a 3-D scan. The dress comes off the printer fully assembled. Other pieces are made with technologies still being developed, such as the laser-welded fabrics from sustainable textile researcher Kate Goldsworthy. The real standouts are in the “Performance” section, which displays attire that uses data from the immediate environment to generate some visible aspect of the garment. These interactive pieces “reveal something to the eye that you wouldn’t see normally, something that science often captures with graphs and charts,” says Pamela Parmal, a curator of the exhibit. For instance, the interactive dress “Incertitudes” is adorned with pins that flex in response to nearby voices, creating waves in the fabric; a dress embedded with thousands of tiny LEDs can display tweeted messages or other illuminated patterns. And there are two leather jackets that, at first glance, look like their innovation is merely a stylish cut. But the jackets are coated in reactive inks that shimmer with iridescent colors in response to the wind and heat generated by heat guns in the display case. (These creations were born after designer and trained chemist Lauren Bowker used the reactive compounds to reveal the aerodynamics of race cars in a wind tunnel in a project for Formula One.)
Visitors seeking in-depth explanations of the science behind the fashions will have to look elsewhere. But “#techstyle” still has something for everyone, whether fashionista or engineer. And while the fashions represented are all cutting edge, the show harks back to an era when clothes were custom-made. Technology might have brought us mass-produced cookie-cutter clothing, but it can also enable clothing tailored to the individual.
From within the dark confines of the skull, the brain builds its own version of reality. By weaving together expectations and information gleaned from the senses, the brain creates a story about the outside world. For most of us, the brain is a skilled storyteller, but to spin a sensible yarn, it has to fill in some details itself.
“The brain is a guessing machine, trying at each moment of time to guess what is out there,” says computational neuroscientist Peggy Seriès. Guesses just slightly off — like mistaking a smile for a smirk — rarely cause harm. But guessing gone seriously awry may play a part in mental illnesses such as schizophrenia, autism and even anxiety disorders, Seriès and other neuroscientists suspect. They say that a mathematical expression known as Bayes’ theorem — which quantifies how prior expectations can be combined with current evidence — may provide novel insights into pernicious mental problems that have so far defied explanation. Bayes’ theorem “offers a new vocabulary, new tools and a new way to look at things,” says Seriès, of the University of Edinburgh.
Experiments guided by Bayesian math reveal that the guessing process differs in people with some disorders. People with schizophrenia, for instance, can have trouble tying together their expectations with what their senses detect. And people with autism and high anxiety don’t flexibly update their expectations about the world, some lab experiments suggest. That missed step can muddy their decision-making abilities. Given the complexity of mental disorders such as schizophrenia and autism, it is no surprise that many theories of how the brain works have fallen short, says psychiatrist and neuroscientist Rick Adams of University College London. Current explanations for the disorders are often vague and untestable. Against that frustrating backdrop, Adams sees great promise in a strong mathematical theory, one that can be used to make predictions and actually test them.
“It’s really a step up from the old-style cognitive psychology approach, where you had flowcharts with boxes and labels on them with things like ‘attention’ or ‘reading,’ but nobody having any idea about what was going on in [any] box,” Adams says.
Applying math to mental disorders “is a very young field,” he adds, pointing to Computational Psychiatry, which plans to publish its first issue this summer. “You know a field is young when it gets its first journal.”
A mind for math Bayesian reasoning may be new to the mental illness scene, but the math itself has been around for centuries. First described by the Rev. Thomas Bayes in the 18th century, this computational approach truly embraces history: Evidence based on previous experience, known as a “prior,” is essential to arriving at a good answer, Bayes argued. He may have been surprised to see his math meticulously applied to people with mental illness, but the logic holds. To make a solid guess about what’s happening in the world, the brain must not rely just on current input from occasionally unreliable senses. The brain must also use its knowledge about what has happened before. Merging these two streams of information correctly is at the heart of perceiving the world as accurately as possible.
Bayes figured out a way to put numbers to this process. By combining probabilities that come from prior evidence and current observations, Bayes’ formula can be used to calculate an overall estimate of the likelihood that a given suspicion is true. A properly functioning brain seems to do this calculation intuitively, behaving in many cases like a skilled Bayesian statistician, some studies show (SN: 10/8/11, p. 18).
This reckoning requires the brain to give the right amount of weight to prior expectations and current information. Depending on the circumstances, those weights change. When the senses falter, for instance, the brain should lean more heavily on prior expectations. Say the mail carrier comes each day at 4 p.m. On a stormy afternoon when visual cues are bad, we rely less on sight and more on prior knowledge to guess that the late-afternoon noise on the front porch is probably the mail carrier delivering letters. In certain mental illnesses, this flexible balancing act may falter.
People with schizophrenia often suffer from hallucinations and delusions, debilitating symptoms that arise when lines between reality and imagination blur. That confusion can lead to hearing voices that aren’t there and believing things that can’t possibly be true. These departures from reality could arise from differences in how people integrate new evidence with previous beliefs. There’s evidence for such distorted calculations. People with schizophrenia don’t fall for certain visual illusions that trick most people, for instance. When shown a picture of the inside of a hollowed-out face mask, most people’s brains mistakenly convert the image to a face that pops outward off the page. People with schizophrenia, however, are more likely to see the face as it actually is — a concave mask. In that instance, people with schizophrenia give more weight to information that’s coming from their eyes than to their expectation that noses protrude from the rest of the face. To complicate matters, the opposite can be true, too, says neuropsychologist Chris Frith of the Wellcome Trust Centre for Neuroimaging at University College London. “In this case, their prior is too weak, but in other cases, their prior is too strong,” he says.
In a recent study, healthy people and those who recently began experiencing psychosis, a symptom of schizophrenia, were shown confusing shadowy black-and-white images. Participants then saw color versions of the images that were easier to interpret. When shown the black-and-white images again, people with early psychosis were better at identifying the images, suggesting that they used their prior knowledge — the color pictures — to truly “see” the images. For people without psychosis, the color images weren’t as much help. That difference suggests that the way people with schizophrenia balance past knowledge and present observations is distinct from the behavior of people without the disorder. Sometimes the balance tips too far — in either direction.
In a talk at the annual Computational and Systems Neuroscience meeting in February in Salt Lake City, Seriès described the results of a different visual test: A small group of people with schizophrenia had to describe which way a series of dots were moving on a screen. The dots moved in some directions more frequently than others — a statistical feature that let the scientists see how well people could learn to predict the dots’ directions. The 11 people with schizophrenia seemed just as good at learning which way the dots were likely to move as the 10 people without, Seriès said. In this situation, people with schizophrenia seemed able to learn priors just fine.
But when another trick was added, a split between the two groups emerged. Sometimes, the dots were almost impossible to see, and sometimes, there were no dots at all. People with schizophrenia were less likely to claim that they saw dots when the screen was blank. Perhaps they didn’t hallucinate dots because of the medication they were on, Seriès says. In fact, very early results from unmedicated people with schizophrenia suggest that they actually see dots that aren’t there more than healthy volunteers. Preliminary results so far on schizophrenia are sparse and occasionally conflicting, Seriès admits. “It’s the beginning,” she says. “We don’t understand much.”
The research is so early that no straightforward story exists yet. But that’s not unexpected. “If 100 years of schizophrenia research have taught us anything, it’s that there’s not going to be a nice, simple explanation,” Adams says. But using math to describe how people perceive the world may lead to new hunches about how that process goes wrong in mental illnesses, he argues.
“You can instill expectations in subjects in many different ways, and you can control what evidence they see,” Adams says. Bayesian theory “tells you what they should conclude from those prior beliefs and that evidence.” If their conclusions diverge from predictions, scientists can take the next step. Brain scans, for instance, may reveal how the wrong answers arise. With a clear description of these differences, he says, “we might be able to measure people’s cognition in a new way, and diagnose their disorders in a new way.”
Now vs. then The way the brain combines incoming sensory information with existing knowledge may also be different in autism, some researchers argue. In some cases, people with autism might put excess weight on what their senses take in about the world and rely less on their expectations. Old observations fit with this idea. In the 1960s, psychologists had discovered that children with autism were just as good at remembering nonsense sentences (“By is go tree stroke lets”) as meaningful ones (“The fish swims in the pond”). Children without autism struggled to remember the non sequiturs. But the children with autism weren’t thrown by the random string of words, suggesting that their expectations of sentence meaning weren’t as strong as their ability to home in on each word in the series.
Another study supports the notion that sensory information takes priority in people with autism. People with and without autism were asked to judge whether a sight and a sound happened at the same time. They saw a white ring on a screen, and a tone played before, after or at the same time. Adults without autism were influenced by previous trials in which the ring and tone were slightly off. But adults with autism were not swayed by earlier trials, researchers reported in February in Scientific Reports.
This literal perception might get in the way of speech perception, Marco Turi of the University of Pisa in Italy and colleagues suggest. Comprehending speech requires a listener to mentally stitch together sights and sounds that may not arrive at the eyes and ears at the same time. Losing that flexibility could make speech harder to understand.
A different study found that children with autism perceive moving dots more clearly than children without autism (SN Online: 5/5/15). The brains of people with autism seem to prioritize incoming sensory information over expectations about how things ought to work. Elizabeth Pellicano of University College London and David Burr of the University of Western Australia in Perth described the concept in 2012 in an opinion paper in Trends in Cognitive Sciences. Intensely attuned to information streaming in from the senses, people with autism experience the world as “too real,” Pellicano and Perth wrote.
New data, however, caution against a too-simple explanation. In an experiment presented in New York City in April at the annual meeting of the Cognitive Neuroscience Society, 20 adults with and without autism had to quickly hit a certain key on a keyboard when they saw its associated target on a screen. Their job was made easier because the targets came in a certain sequence. All of the participants improved as they learned which keys to expect. But when the sequence changed to a new one, people with autism faltered. This result suggests that they learned prior expectations just fine, but had trouble updating them as conditions changed, said cognitive neuroscientist Owen Parsons of the University of Cambridge. Distorted calculations — and the altered versions of the world they create — may also play a role in depression and anxiety, some researchers think. While suffering from depression, people may hold on to distorted priors — believing that good things are out of reach, for instance. And people with high anxiety can have trouble making good choices in a volatile environment, neuroscientist Sonia Bishop of the University of California, Berkeley and colleagues reported in 2015 in Nature Neuroscience.
In their experiment, people had to choose a shape, which sometimes came with a shock. People with low anxiety quickly learned to avoid the shock, even when the relationship between shape and shock changed. But people with high anxiety performed worse when those relationships changed, the researchers found. “High-anxious individuals didn’t seem able to adjust their learning to handle how volatile or how stable the environment was,” Bishop says. Scientists can’t yet say what causes this difficulty adjusting to a new environment in anxious people and in people with autism. It could be that once some rule is learned (a sequence of computer keys, or the link between a shape and a shock), these two groups struggle to update that prior with newer information.
This rigidity might actually contribute to anxiety in the first place, Bishop speculates. “When something unexpected happens that is bad, you wouldn’t know how to respond,” and that floundering “is likely to be a huge source of anxiety and stress.”
Recalculating “There’s been a lot of frustration with a failure to make progress” on psychiatric disorders, Bishop says. Fitting mathematical theories to the brain may be a way to move forward. Researchers “are very excited about computational psychiatry in general,” she says.
Computational psychiatrist Quentin Huys of the University of Zurich is one of those people. Math can help clarify mental illnesses in a way that existing approaches can’t, he says. In the March issue of Nature Neuroscience, Huys and colleagues argued that math can demystify psychiatric disorders, and that thinking of the brain as a Bayesian number cruncher might lead to a more rigorous understanding of mental illness. Huys says that a computational approach is essential. “We can’t get away without it.” If people with high anxiety perform differently on a perceptual test, then that test could be used to both diagnose people and monitor how well a treatment works, for instance.
Scientists hope that a deeper description of mental illnesses may lead to clearer ways to identify a disorder, chart how well treatments work and even improve therapies. Bishop raises the possibility of developing apps to help people with high anxiety evaluate situations — outsourcing the decision making for people who have trouble. Frith points out that cognitive behavioral therapy could help depressed people recalculate their experiences by putting less weight on negative experiences and perhaps breaking out of cycles of despondence.
Beyond these potential interventions, simply explaining to people how their brains are working might ease distress, Adams says. “If you can give people an explanation that makes sense of some of the experiences they’ve had, that can be a profoundly helpful thing,” he says. “It destigmatizes the experience.”
Our home planet is young at heart. According to new calculations, Earth’s center is more than two years younger than its surface.
In Einstein’s general theory of relativity, massive objects warp the fabric of spacetime, creating a gravitational pull and slowing time nearby. So a clock placed at Earth’s center will tick ever-so-slightly slower than a clock at its surface. Such time shifts are determined by the gravitational potential, a measure of the amount of work it would take to move an object from one place to another. Since climbing up from Earth’s center would be a struggle against gravity, clocks down deep would run slow relative to surface timepieces. Over the 4.5 billion years of Earth’s history, the gradual shaving off of fractions of a second adds up to a core that’s 2.5 years younger than the planet’s crust, researchers estimate in the May European Journal of Physics. Theoretical physicist Richard Feynman had suggested in the 1960s that the core was younger, but only by a few days. The new calculation neglects geological processes, which have a larger impact on the planet’s age. For example, Earth’s core probably formed earlier than its crust. Instead, says study author Ulrik Uggerhøj of Aarhus University in Denmark, the calculation serves as an illustration of gravity’s influence on time — very close to home.
The green hairstreak butterfly (Callophrys rubi) gets its blue-green hue from complex nanoscale structures on its wings. The structures, called gyroids, are repeating patterns of spiral-shaped curls. Light waves bouncing off the patterned surface (top inset above) interfere with one another, amplifying green colors while washing out other shades (SN: 6/7/08, p. 26).
Scientists led by Min Gu of the Royal Melbourne Institute of Technology in Australia have now painstakingly re-created the gyroid structure by sculpting the shapes out of a special resin that solidifies when hit with laser light. The technique, called optical two-beam lithography, uses a pair of lasers to set the material in just the right pattern. Afterward, the remaining resin can be washed away, leaving only the gyroid structure. The fabricated version repeats its pattern every 360 nanometers, or billionths of a meter.
The gyroid structures determine more than just color. They also divvy up light that is circularly polarized — its electric fields spiral either clockwise or counterclockwise. In the butterfly, this effect is weak because of irregularities in the structure. But the artificial version sorts the light according to polarization, reflecting one type much more than the other, the researchers report May 13 in Science Advances.
The ability to control circular polarization of light with structures like these could allow scientists to increase the bandwidth of optical communications, the researchers say. The two polarizations of light could each carry different information, which could then be separated and decoded down the line.
Everyone ages. Growing old is a fundamental feature of human existence.
Though we might not always be aware of aging, it looms in all of our futures. As Science News editor in chief Eva Emerson writes, “Aging happens to each of us, everywhere, all the time. It is so ever-present and slow that we tend to take little notice of it. Until we do.”
But, our scientific understanding of aging pales in comparison to its significance in our lives. While new studies reveal exciting prospects for slowing the effects of aging, its causes and extensive effects remain enigmatic. Scientists are still divided on some fundamentals of aging, and that’s why aging research raises some interesting questions. For example, how does it change the brain? How did different life histories evolve? How old is the oldest blue whale? This special report addresses those questions and more.
